In the year 1873, a Japanese woman is sold as a mistress to an American diplomat stationed in Japan.

Monjiro, reunited with his long lost sister, is pursued by a yakuza gang because he killed their boss. He also meets a fellow gambler who idolizes Monjiro. The gambler and Monjiro's sister are pulled into a conspiracy to get to Monjiro, but do things go as planned?

Natsuko is so good at using that super-strong vagina of hers that she can fuck guys to death. In the end, she’s pitted against a sexual superman and a showdown ensues. There’s also a subplot about a mad scientist type who needs vaginal juices to create a potion designed to turn Japanese girls black.

In this outing of Harenchi Gakuen the students undergo a health check after school, but all is not what it seems. Teacher 'Beard Godzilla' has kicked out the infirmary's doctor and taken his place. A trio of students notice the trick and dress up as medical professionals to assist the female portion of the school body. A newspaper has caught wind of this.