Time to put on your party hats and dancing shoes - D.W. is turning five! When her birthday doesn't go as planned, D.W. runs away to the magical island of Ukubonga. Meanwhile, Arthur has skipped her birthday party to go on a school trip to the planetarium - but instead of transporting him into outer space, it transports him 4 years into the future! This is one party you don't want to miss.

When the prospect of an Elwood City concert by the Backstreet Boys drives everyone else into a frenzy, a disgusted Francine decides to counter with an "anti-cute" band of her own called U Stink. But things don't go quite the way she had planned.

The show revolves around the lives of 8-year-old Arthur Read, an anthropomorphic aardvark, his friends and family, and their daily interactions with each other.

A CIA agent infiltrates the research team of a scientist who seeks to capture the essence of a dying leukemia patient.