During the course of his experiments at the Institute of Sexual Research, Dr. Charles Cherrypopper comes up with a rather interesting device... the Electro-Testicular Cock-Erector, which will cause every man in the nation to suffer an instant and unbelievable erection! The good doctor has a plan to put the device into action, and in the resulting confusion, take over the government! But, our heroine, Penelope Juiceslit, has other ideas, and sets out to stop the wicked doctor before it's too late.

After dumping his pregnant girlfriend, an arrogant chauvinist is hit by a van and reincarnated as a woman.