In San Francisco, Jill Valentine is dealing with a zombie outbreak and a new T-Virus, Leon Kennedy is on the trail of a kidnapped DARPA scientist, and Claire Redfield is investigating a monstrous fish that is killing whales in the bay. Joined by Chris Redfield and Rebecca Chambers, they discover the trail of clues from their separate cases all converge on the same location, Alcatraz Island, where a new evil has taken residence and awaits their arrival.

A senior living facility is the home of one special family who holds the key to immortality among its elderly residents. Their younger, abusive employees are now the ones living on Borrowed Time.

Bucum Jackson (Cube) is a bounty hunter with a lot of attitude and no interest in taking on a partner. Working at Martinez Bail Bonds, Jackson has unorthodox methods of tracking down low-life criminals, but they work, and one day he hopes to become his own boss and open up his own private investigation firm. Reggie Wright (Epps) is a slippery con artist who is avoiding the law, and Jackson. During a cat and mouse chase, the two stumble on a multi-million dollar diamond heist. Hiding from Jackson, Wright finds himself in the thieves' getaway van and ends up having to escape from them after they discover their booty is fake, much to the displeasure of their ruthless boss (Flanagan). When Wright meets up with his girlfriend (Mendes), he discovers that his recently purchased lottery ticket is the sole winner of $60 million. Unfortunately, his wallet, which held the ticket, was left in the thieves' van, so he persuades Jackson to help him get it back.