Based on Howard Waldrop's 1987 sci-fi novel.

Jim Hanson’s quiet life is suddenly disturbed by two people crossing the US/Mexico border – a woman and her young son – desperate to flee a Mexican cartel. After a shootout leaves the mother dead, Jim becomes the boy’s reluctant defender. He embraces his role as Miguel’s protector and will stop at nothing to get him to safety, as they go on the run from the relentless assassins.

Successful businessman Jake takes his pregnant girlfriend Lindsey on a babymoon trip to an upscale desert resort. When they get there, Lindsey discovers thatJake’s meddlesome soon to be ex-wife, Gwen is there too. In a dream vacation gone wrong, it becomes apparent that someone is determined that Lindsey will never use her return ticket.

Ray Owens is sheriff of the quiet US border town of Sommerton Junction after leaving the LAPD following a bungled operation. Following his escape from the FBI, a notorious drug baron, his gang, and a hostage are heading toward Sommerton Junction where the police are preparing to make a last stand to intercept them before they cross the border. Owens is reluctant to become involved but ultimately joins in with the law enforcement efforts

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.