Tom, greeting-card writer and hopeless romantic, is caught completely off-guard when his girlfriend, Summer, suddenly dumps him. He reflects on their 500 days together to try to figure out where their love affair went sour, and in doing so, Tom rediscovers his true passions in life.

The series picks up four years after the events of Terminator 2: Judgment Day with John and Sarah Connor trying to stay under-the-radar from the government, as they plot to destroy the computer network, Skynet, in hopes of preventing Armageddon.

Newlywed Melinda Gordon tries to help the dead communicate with loved ones, but sometimes the messages she receives are intense and confusing. Most of Melinda's efforts involve resolving conflicts that are preventing the spirits from passing over.