Madison Avenue executive Graham Marshall has paid his dues. A talented and devoted worker, he has suffered through mounting bills and a nagging wife with one thing to look forward to: a well-deserved promotion. But when the promotion is given to a loud-mouthed yuppie associate, Graham unleashes his rage on an overly aggressive panhandler, who he accidently kills by pushing him into the path of an oncoming subway train. He re-thinks his problems with an entirely new solution. First, he arranges an "accident" for his annoying wife. Then he creates another "mishap" for his boss. It seems like the world is once more Graham's oyster…but a missing cigarette lighter and a prying police detective may change all that.

Dr. Anansa Linderby is kidnapped in a medical mission in Africa by a slave trader. From this moment, her husband will do anything to recover her and to punish the bad guys, but that will be not an easy task.

After the events of The African Queen (1951), Charlie and Rose are recaptured by the Germans and forced to tug one of their big cannons that could bring the Nazis victory against the local Allied forces.