On a desolate, Midwestern county road, a bound man crawls towards a remote postal box, managing to slide a blood-stained plea-for-help message into the slot before a panicking figure closes in behind him. The note makes its way to the county post office and onto the desk of Jasper, a seasoned and skilled 'dead letter' investigator, responsible for investigating lost mail and returning it to its sender. As he investigates further, Jasper meets Trent, a strange yet unassuming man who has taken up residence at the men’s home where Jasper lives. When Trent unexpectedly shows up at Jasper’s office, it becomes clear he has a vested interest in the note, and will stop at nothing to retrieve it.

Starting over isn’t easy, especially for small-town guy John Nolan who, after a life-altering incident, is pursuing his dream of being an LAPD officer. As the force’s oldest rookie, he’s met with skepticism from some higher-ups who see him as just a walking midlife crisis.

Ian Murphy can't find a job. Layla is facing harassment at her job. At home, the two of them can't seem to connect anymore. After one faithful night, she walks out on him leaving him distraught, angry, and self loathing. Through some cosmic shift, he meets Evelyn, who is impossibly positive and helps make life seem bearable for him again.

In a last ditch effort to save their marriage, Nick and Willa visit a renowned, yet eccentric, couples therapist and embark on a month-long journey of provocative and hilarious sex assignments.