An intuitive young neurosurgeon discovers that she is the unlikely heir to a family of witches. As she grapples with her newfound powers, she must contend with a sinister presence that has haunted her family for generations.

Joe—a down-on-his-luck truck driver haunted by the memory of his deceased wife and child—meets Julie, a spiritually gifted woman who enlists his help in a desperate effort to find the lost soul of her comatose daughter. But the spirit of Joe's dead wife proves stronger, possessing the young woman's body and determined to settle her unfinished business with the living.