T.H.E.Y. has programmed Sandra West to become a T.H.E.Y. assassin. Can Superseven stop her from killing more agents and prevent her head from exploding like a poodle in a microwave?

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.