Ron and Casey are expecting a child, but things get out of hand when they both try to protect each other from an inevitable break-up.

William Masters and Virginia Johnson are real-life pioneers of the science of human sexuality. Their research touched off the sexual revolution and took them from a midwestern teaching hospital to the cover of Time magazine and multiple appearances on Johnny Carson's couch. He is a brilliant scientist out of touch with his own feelings, and she is a single working mother ahead of her time. The series chronicles their unusual lives, romance, and unlikely pop culture trajectory.

After thirty years of marriage, a middle-aged couple attends an intense, week-long counseling session to work on their relationship.