Sam Giancana is a ruthless mob boss from Chicago. During a trip to Las Vegas, he sees a performance by the McGuire Sisters, a popular singing group with a pure image. Sam is attracted to Phyllis and begins aggressively courting her. The two enter into an epic romance, but it brings unwanted attention and tarnishes Phyllis's reputation. For Sam, however, the consequences are far more drastic, landing him in trouble with the law and his fellow mobsters.

Hosted by Bill Kurtis, American Justice looks at groundbreaking criminal cases, presenting viewers with an inside look at the case through the eyes of those directly involved, ranging from law enforcement officers to the victims.

With archive film including home movies and FBI surveillance material, the award-winning Crime Inc. tells the true story behind the world's most powerful crime syndicate, the Mob, La Cosa Nostra or The Mafia. Interviews with mob members turned informants, including former boss Jimmy 'The Weasel' Fratianno, reveal the inner workings of the mafia, from the ritual of becoming a "made" man and their code of honor, to the harrowing and detailed descriptions of their work, accompanied by equally graphic images and film footage.