A good looking, but shy man with a tragically small penis takes a fringe herbal remedy that makes him grow and grow and grow.

Richard Jones a fast talking ladies man who wakes up one morning and discovers something incredible, HIS PENIS IS GONE! Desperate and freaked out, Richard seeks the help of a Voodoo Priestess who tells him that one of the women in his past has placed a powerful curse on him. Even worse, if he doesn't track down this women and retrieve his penis before midnight the hex will be irreversible. Now, racing against time, Richard has to revisit the countless girls that he has conned in the past and figure out which one stole his manhood.

In his basement in San Francisco, boy-genius Quinn Mallory unlocks the doorway to an infinite number of Earths. During a test run, Quinn invites co-worker Wade Welles and his teacher Professor Maximillian Arturo to see his new invention. But an increase in power and an early departure leave all three, plus a washed-up soul singer named Rembrandt "Crying Man" Brown, lost in a parallel world. Now they must "slide" from world to world, not only adapting to their changing surroundings, but also trying to get back to their world. Will they ever make it home?