On the occasion of the birthday feast of Queen Wu Zetian, it was suddenly reported that the "red-eyed monster" was committing a chaotic case, and Wu Zetian ordered Di Renjie to supervise the case. Di Renjie and his apprentice Chen Jiangqiao came to Fangzhou to investigate the case, and chanced upon Shen Qingqing, who was also investigating the case. Through the investigation of the case, the trio gradually approached the truth behind the "red-eyed monster", which led to a series of serial incidents. In the process of dealing with this series of incidents, Di Renjie was upright, putting the common people of Li people first, and expressing a sense of responsibility and mission that "everyone is responsible for the rise and fall of the world", and finally successfully solved the mystery.

On her wedding day, Chu Jiuling (daughter of former crown prince) discovers that the person who killed her father is her uncle (the current Emperor). Just as she decides to seek revenge, she was almost killed by her husband, an imperial guard. Fortunately, she was saved by physician Zhang Qingshan. Chu Jiuling returns with a new identity - Jun Zhenzhen and assists the Fang family in unraveling the schemes of the Emperor, saving them from becoming victims of a political scheme. With her outstanding medical skills and wit, she then changed her name to Jun Jiuling, and heads to the capital to become a physician. After managing to integrate with royalty, she sets out to unravel corruptions behind the political court and win the hearts of people.

Renhe Hospital nurse Zhang Shumei is forced to resign after being suspected of accidentally killing a patient. Zhang Shumei’s 4 year old daughter is abducted, and she herself dies in a car accident a couple of years later. 30 years later, Zhang Shumei’s son Zhuang Shu returns to the hospital as a surgeon who is intent on unraveling the secret behind his family’s misfortune.

Based on a true story about great robbery of the tombstone treasure in 1938, which marked the end of the King dynasty in China.