"Patterns" was an American television play broadcast live on January 12, 1955, remade as a film the next year with some of the same cast. Fred Staples is the newest executive in a large firm. He strikes up a friendship with Andy Sloane, the Vice President to whom he nominally reports. Staples is good at his job and the company's hard-nosed president, Walter Ramsey, is pleased with his choice. Staples has a crisis of conscience when Ramsey tells him that he's been recruited to replace Sloane, someone who has devoted his entire life to the company at the expense of his family. Sloane knows what Ramsey is up to but digs in his heels and refuses to quit. Tragedy ensues forcing Staples to make a choice.

A dramatized story about a town where illegal activities are allowed to thrive, some of the politicians are dishonest, and a doctor and couple of colleagues try to help townspeople see that public health measures, especially those that might control syphilis, are necessary. Two of the most influential men in town oppose clean-up and public health efforts until their young adult children contract syphilis. Spliced into the dramatic film are segments of other educational films, including animated segments, that describe the symptoms and risks of syphilis. A butcher named Tony is excited about the birth of his first child, but the child is born dead because of a maternal syphilis infection.

After hearing that a famous actress is dying in a hospital after being hit by a car, a reporter goes to the hospital to interview the actress. She then tells the reporter that her wealthy fiance, who was killed in an accident several years before, was actually murdered. Before long the reporter finds herself in a web of corruption, mental illness and murder.