Jack is a divorced, ex CIA agent, living in his disabled father's home (Jeff the Drunk from the Howard Stern Show), His daughter Sharon, wants to become an actress and needs her father's signature permission to fly to Hollywood for Black Casting Couch Auditions, where she eventually gets kidnapped by ISIS. They Kidnapped the Wrong Daughter, as her father Jack, possesses a particular set of skills.

It has taken 10 years, two little Fockers with wife Pam and countless hurdles for Greg to finally get in with his tightly wound father-in-law, Jack. After the cash-strapped dad takes a job moonlighting for a drug company, Jack's suspicions about his favorite male nurse come roaring back. When Greg and Pam's entire clan descends for the twins' birthday party, Greg must prove to the skeptical Jack that he's fully capable as the man of the house.