Two wealthy Roman sisters, Marina and Sabrina, the first betrayed wife of a homosexual surgeon, the second left by her multi-horned husband, escape from their respective failures and take a vacation at Circeo, in a splendid villa by the sea. With them there is also Lorena, Marina's masseuse, who has also returned from a sentimental disappointment, and after a few days they are joined by Caterina, the third sister, costume designer for the cinema. She decided each of her in her own way to solve her problems with men, they will end up victims of a seducer and scoundrel writer, but they will always know how to get back on their feet.

Single and middle-aged, beautiful Irene (Margarita Buy) is wholly devoted to her job as an inspector of luxury hotels. Constantly on the road, she indulges in expensive pleasures at impeccable resorts, but always incognito and alone, soon escaping to the next exotic destination with her checklist and laptop in tow. When her best friend and ex, Andrea (Stefano Accorsi), who has always been a source of emotional support, suddenly becomes unavailable, Irene is thrown into a deep existential crisis. "Luxury is a form of deceit," she is told by a fellow traveller in the fog of a steam room, and thus begins Irene's quest to bring more meaning into her life.