Zeke, a writer struggling to finish his novel after the death of a loved one, is befriended by an unlikely stranger.

In post-9/11 New York City, an eclectic group of citizens find their lives entangled, personally, romantically, and sexually, at Shortbus, an underground Brooklyn salon infamous for its blend of art, music, politics, and carnality.

Two unlikely buddies spend a day in New York in pursuit of sex and drugs.