Billy Hill and Jack 'Spot' Comer were among the most notorious criminals in London up until the 1950s. Dramatising the violent reign of two of London's most notorious gangsters, Billy Hill (Leo Gregory) and Jack 'Spot' Comer (Terry Stone), ONCE UPON A TIME IN LONDON charts the legendary rise and fall of a nationwide criminal empire that lasted until the mid-fifties and which paved the way for the notorious Kray Twins and The Richardsons. This is the story of their rise and fall.

In an alternative future in which the Cold War never ended, a man called David, flees the city with his pregnant wife, Abigail, in search of freedom.

A successful young author begins experiencing visions through her dreams, she begins having psychic connections to an ancient race of lycanthropes responsible for several unsolved murders in a small coastal town.