When Stephanie, a famous violinist, contracts multiple sclerosis her life begins to fall apart. Her career ends, her husband leaves her for another woman and her favorite pupil leave the country. Unable to bear all this loss, Stephanie attempts suicide.

Bob Crane has long maintained a psychic connection to his twin sister, Jessica, who works as a fashion model in Milan. When Bob senses that his sister might be injured or killed, he travels to Italy to look for her, only to discover that she's vanished without a trace. Enlisting the help of about-to-retire Commissioner Danesi, Bob soon finds himself embroiled in a web of mystery and terror, when a scissors wielding killer begins to strike and all clues lead back to Jessica...