Tracy Wainwright is a young graphic artist at an Internet company in San Francisco. Mrs. Jones, the company's hard-as-nails CEO, takes a liking to Tracy and begins to seduce him by giving him lavish gifts while he becomes her personal love slave. When Tracy meets the love of his life, Desiree, he ultimately must choose between the two women.

Perhaps their strikingly different personalities make the relationship between detective Jane Rizzoli and medical examiner Maura Isles so effective. Jane, the only female cop in Boston's homicide division, is tough, relentless and rarely lets her guard down, while the impeccably dressed Maura displays a sometimes icy temperament — she is, after all, more comfortable among the dead than the living. Together, the best friends have forged a quirky and supportive relationship; they drop the protective shield in each other's company, and combine their expertise to solve Boston's most complex cases.