Maggie Cole is a research scientist who, after the sudden death of her husband, takes a position as an on-call doctor in an inner-city clinic. There, she must fight a battle on two fronts: against the medical conditions endangering her patients and against sexism toward a female doctor.

Arizona Territorial Prison inmate Paris Pitman, Jr. is a schemer, a charmer, and quite popular among his fellow convicts — especially with $500,000 in stolen loot hidden away and a plan to escape and recover it. New warden Woodward Lopeman has other ideas about Pitman. Each man will have the tables turned on him.

George & Gwen Kellerman make a trip to New York, where George is going to start a new job, it turns out to be a trip to hell.