Two New Orleans detectives become embroiled in a centuries-long feud between two secretive factions of vampires while investigating a runaway child's case. Torn between their everyday lives and the dangerous lure of immortality, the detectives must race to destroy the evil Moldero clan.

Upon the death of his great grandfather, Brandon Davis - a wedding photographer - inherits an antique camera famous for taking Victorian death photography. After photographing his subjects they start to die from horrible, bizarre deaths.