A family loaded with quirky, colorful characters piles into an old van and road trips to California for little Olive to compete in a beauty pageant.

The eccentric and childish Pee-wee Herman embarks on a big adventure when his beloved bicycle is stolen. Armed with information from a fortune-teller and a relentless obsession with his prized possession, Pee-wee encounters a host of odd characters and bizarre situations as he treks across the country to recover his bike.

God appears before 11-year-old Tracy Richards to ask for her help to spread his word and influence over the world which she suggests the slogan 'Think God.' Naturaly, Tracy's divorced parents think Tracy's crazy, and plot to halt her 'heaven-sent' mission to spread God's word.

In preparation for his daughter's wedding, dentist Sheldon Kornpett meets Vince Ricardo, the groom's father. Vince, a manic fellow who claims to be a government agent, then proceeds to drag Sheldon into a series of chases and misadventures from New York to Central America.

An awkward, telekinetic teenage girl's lonely life is dominated by relentless bullying at school and an oppressive religious fanatic mother at home. When her tormentors pull a humiliating prank at the senior prom, she unleashes a horrifying chaos on everyone, leaving nothing but destruction in her wake.