Rick, a dope fiend, believes his goal in life is to track down Ginger, a famous porn star who is currently staying in her Beverly Hills hideaway. Rick is obsessed with Ginger, watches her movies obsessively, and deals drugs on the side, all to the chagrin of his lover Tamara. He decides to seek out Ginger while on the road, and along the way picks up Jules, a neurotic virgin.

Tweeked is the story of Carrie and Michelle, whose friendship disintegrates as they careen into a methamphetamine frenzy.

When troubled teen boy Stevie (Cameron Van Hoy) and his girlfriend, Rocky (Mischa Barton), attempt to rob a bank without any forethought, the situation rapidly deteriorates. Soon the young couple is holding bank customers and employees hostage, while law enforcement gathers outside. Daniel Bender (Burt Reynolds), a veteran negotiator for the FBI, is charged with assessing the crime scene and ending the standoff as quickly as possible, but Stevie's short fuse considerably complicates matters.

A young woman in L.A. is having a bad day: she's evicted, an audition ends with a producer furious she won't trade sex for the part, and a policeman nabs her for something she didn't do, demanding fellatio to release her. She snaps, grabs his gun, takes his uniform, and leaves him cuffed to a tree where he's soon having a defenseless chat with a homeless man. She takes off on the cop's motorcycle and, for an afternoon, experiences a cop's life. She talks a young man out of suicide and then is plunged into violence after a friendly encounter with two "vatos." She is torn between self-protection and others' expectations. Is there any resolution for her torrent of feelings?