The film tells the life of the young Genoese poet and patriot Goffredo Mameli, who died in battle in Rome at the age of 21, in 1849. In addition to being one of the main exponents of the Risorgimento.

In the exact moment they hit rock bottom, four strangers are visited by a mysterious man who gifts them a week to see how the world would be without them.

Aspiring writer Tommaso makes a living by penning the self-help column of a women's magazine. One day he receives a letter from a reader asking for advice on how to break up with her man: it is none other than Zoe, his partner of ten years, unaware of his pseudonymous side job. Tommaso can't believe his eyes and answers her in private to learn more.

Six stories about childhood, set in six different decades, from the 50s to today, bound to each other by a mystery.