In 1960, Martín and Marcos are forced by their difficult personal circumstances to travel to Switzerland in search of work, leaving their families in the Madrid of Franco's Spain. But they undertake more than a simple journey; they begin the road to a new life.

Three women from three different generations and walks of life find themselves in a very hot, semi-deserted Spanish town. Patricia is a 17 year old roaming Spain in search for a certain man; Sol is 27, a door-to-door salesgirl in dire economic straits who has just been thrown out of her apartment; and Virginia is a middle aged housewife, who after 20 years decides to start a new life. These three spend a very unique 24 hour period together, often acting, as the title suggests, as modern day "witches".

After being estranged for 15 years, flamboyant actress Becky del Paramo re-enters her daughter Rebeca's life when she comes to perform a concert. Rebeca, she finds, is now married to one of Becky's ex-lovers, Manuel. The mother and daughter begin making up for lost time, when suddenly, a murder occurs...