Celebrated sleuth Hercule Poirot, now retired and living in self-imposed exile in Venice, reluctantly attends a Halloween séance at a decaying, haunted palazzo. When one of the guests is murdered, the detective is thrust into a sinister world of shadows and secrets.

London, June 29th, 1613. The Globe Theater, ran by the famous playwright William Shakespeare, accidentally burns to ashes. Seriously affected, he stops writing and returns to his hometown, where his wife Anne and daughters Judith and Susanna get surprised to hear he intends to stay there definitively, after two decades working in the capital, neglecting his sincere affections for them.