While caring for her brother along with her audacious mother, a teenager strikes up an unlikely friendship with an eccentric activist who is protesting one of the most landmark medical cases of all time.

Lena, a troubled youth takes a white lion cub under her wing; little does she know the lion escaped from criminals intended to take the cub to an evil trophy hunter named Ben Percy.

Shaun Murphy, a young surgeon with autism and savant syndrome, relocates from a quiet country life to join a prestigious hospital's surgical unit. Unable to personally connect with those around him, Shaun uses his extraordinary medical gifts to save lives and challenge the skepticism of his colleagues.

Los Angeles. 1983. A storm is coming and its name is crack. Set against the infancy of the crack cocaine epidemic and its ultimate radical impact on the culture as we know it, the story follows numerous characters on a violent collision course.