Jack Shepard is an out-of-shape auto shop owner, far removed from the man who once protected the world's freedom. Reluctantly called back into action by the government, Jack is tasked with turning a ragtag group of kids with special powers into a new generation of superheroes to save the world from certain destruction.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.