A young artist, imprisoned within the trammels of opium addiction, relives his phantasmagorical courtship with a mysterious Soprano known only as Ligeia. While exploring these opium induced memories, the lines dividing reality and fantasy, memory and hallucination, begin to blur into an indecipherable labyrinth of obsession and despair. Though he is nursed back to health by a new love, the Lady Rowena, the haunting of Ligeia's memories as well as the spirits of Azrael and Nehushtan, continue to plague his mind and soul.

Barney Ross leads a band of highly skilled mercenaries including knife enthusiast Lee Christmas, a martial arts expert Yin Yang, heavy weapons specialist Hale Caesar, demolitionist Toll Road, and a loose-cannon sniper Gunner Jensen. When the group is commissioned by the mysterious Mr. Church to assassinate the dictator of a small South American island, Barney and Lee visit the remote locale to scout out their opposition and discover the true nature of the conflict engulfing the city.