After fighting his demons for decades, John Rambo now lives in peace on his family ranch in Arizona, but his rest is interrupted when Gabriela, the granddaughter of his housekeeper María, disappears after crossing the border into Mexico to meet her biological father. Rambo, who has become a true father figure for Gabriela over the years, undertakes a desperate and dangerous journey to find her.

Inspired by one of the longest and bloodiest real-life events in police history, Officer Mike Chandler and a young civilian passenger find themselves under-prepared and outgunned when fate puts them squarely in the crosshairs of a daring bank heist in progress by a fearless team of highly-trained and heavily-armed men.