Harvard symbologist Robert Langdon is recruited by the Vatican to investigate the apparent return of the Illuminati - a secret, underground organization - after four cardinals are kidnapped on the night of the papal conclave.

Dr. Jacob Hood is a brilliant biophysicist and special science advisor to the government who investigates scientific crises and oddities. His crusade is to protect the substance of science against those who would abuse and misuse scientific discoveries for their own gain.

CSI: Miami follows Crime Scene Investigators working for the Miami-Dade Police Department as they use physical evidence, similar to their Las Vegas counterparts, to solve grisly murders. The series mixes deduction, gritty subject matter, and character-driven drama in the same vein as the original series in the CSI franchise, except that the Miami CSIs are cops first, scientists second.