A drama about a multi-generational family of cops dedicated to New York City law enforcement. Frank Reagan is the New York Police Commissioner and heads both the police force and the Reagan brood. He runs his department as diplomatically as he runs his family, even when dealing with the politics that plagued his unapologetically bold father, Henry, during his stint as Chief.

Three friends persecute a gang of criminals from Harlem to the parties of the High Society of London.

Sheena's parents are killed while on Safari. She is raised by the mystical witch woman of an African tribe. When her foster mother is framed for the murder of a political leader, Sheena and a newsman, Vic Casey, are forced to flee while pursued by the mercenaries hired by the real killer, who hopes to assume power. Sheena's ability to talk to the animals and knowledge of jungle lore give them a chance against the high tech weapons of the mercenaries.