After Pompey's defeat at the Battle of Farsalia, Julius Caesar becomes the beacon of the Roman Republic and the master of its destiny; but many patricians want to avoid the birth of a tyranny and plot to assassinate him…

Kingdom of Hawaii, 1866. Fearful that leprosy would spread throughout the archipelago, the king banishes the sick to the island of Molokai. In 1873, the Belgian Catholic missionary Damien de Veuster arrives on the island to help improve the lives of its unfortunate inhabitants.