Amiable con man Jack Cooper is on a westbound stagecoach, headed for the next batch of suckers who will mistake him for an easy mark. Fiery Sarah O'Rourke rides the same coach, handcuffed to lawman Bill Speakes and headed for the hangman. In a few hours, all should reach their destinations. But the trail they travel takes an unexpected turn: Cooper and O'Rourke are soon off the stage and running for their lives. The law ends and the chase begins in a very alive tale of wanted-dead-or-alive fugitives (Linda Fiorentino and Craig Sheffer) pursued by a marshal (Sam Elliott) who's a law unto himself.

Lucky Luke becomes the Sheriff of Daisy Town and runs out all the criminals. Then the Dalton brothers arrive and try to get the Indians to break the peace treaty and attack the town.