A talk-radio host, who specializes in abusing and insulting his audience, gets a call from a disturbed teenage girl who says she is going to commit suicide. After first encouraging her, he has a change of heart and frantically tries to get his listeners to help find the girl before she makes good on her threat.

Chaos ensues when two former college friends, one a housewife and the other the editor of a hip women's magazine, decide to swap lifestyles between them.