When a serial killer is targeting prostitutes and draining their blood, a detective and his unusual new partner must try to solve the case before another young woman is killed.

A sexually transmitted disease causes students to drop dead at an alarming rate on a Midwest campus. When Cameron discovers his girlfriend is the first victim, he becomes the first suspect.

Dylan, a young man working at a funeral parlor, is trying to unravel a mystery that shattered his life ten years earlier. After faking his own funeral to see who will show up, he befriends a mysterious street junkie and is reunited with an old love from his past. The lives of these three characters are transformed by supernatural forces as Dylan discovers that no one is who they seem to be.

Professor David Salt's guilty secrets draw him to the fabled town of Villisca. Past and present collide as he is driven to help the trapped spirits and seek his own redemption.