A hitman accidentally kills a little girl. Filled with regret, he wants to quit. But then to tie up loose ends, he is forced to go on another job, to kill the girl's mother.

Joseph is the youngest member of a large family that owns a successful garment business in Los Angeles. His father, Jacob, makes no attempt at hiding the fact that Joseph is his favorite son, resulting in the constant envy and resentment of his brothers. Eventually, in their bitterness, they plot revenge against this favored son. When Joseph accompanies his brothers on a trip to New York, they commit the ultimate betrayal, stranding him there, a virtual prisoner in a corrupt, modern-day sweat shop.

ER explores the inner workings of an urban teaching hospital and the critical issues faced by the dedicated physicians and staff of its overburdened emergency room.