Marcus Burnett is a henpecked family man. Mike Lowry is a footloose and fancy free ladies' man. Both Miami policemen, they have 72 hours to reclaim a consignment of drugs stolen from under their station's nose. To complicate matters, in order to get the assistance of the sole witness to a murder, they have to pretend to be each other.

May Munro is a woman obsessed with getting revenge on the people who murdered her parents when she was still a girl. She hires Ray Quick, a retired explosives expert to kill her parent's killers. When Ned Trent, embittered ex-partner of Quick's is assigned to protect one of Quick's potential victims, a deadly game of cat and mouse ensues.