Nathalie and Louise are friends from childhood. While studying drama at University Louise becomes hopelessly obsessed with her friend. Jealous of the male friends she has she breaks up the friendship, followed by a suicide attempt. Later, Louise marries, but finds time to see the, by now quite accomplished actress, Nathalie. They fight through the years, La Repetition following them as their friendship comes together and breaks up frequently, while never actually reaching anything that can be called a climax.

After the arrest of his mother, who is accused of collaboration, 14-year-old Theo decides to go join his grandfather in Paris. On the road he meets Marie, an 11 year old orphan.

The series follows the adventures of lighthearted Jean-Paul Moulin, a police Commissaire, and his team as they solve crimes.