Samuel Pierret is a nurse who saves the wrong guy – a thief whose henchmen take Samuel's pregnant wife hostage to force him to spring their boss from the hospital. A race through the subways and streets of Paris ensues, and the body count rises. Can Samuel evade the cops and the criminal underground and deliver his beloved to safety?

When the coach of the France soccer team is killed by a poisoned dart in the stadium in the end of a game, and his expensive and huge ring with the diamond Pink Panther disappears, the ambitious Chief Inspector Dreyfus assigns the worst police inspector Jacques Clouseau to the case.