Maya Dolittle is back in a heartwarming adventure of presidential proportions! Maya's dream of going to vet school is put on hold when she gets a call from the president of the United States. It seems the First Dog is out of control, and the president needs Maya's help. It's up to Maya and her own dog, Lucky, to stop a canine catastrophe from becoming a national crisis!

Cursed since childhood, dentist Charlie Logan cannot find the right woman. Even worse, he learns that each of his ex-girlfriends finds true love with the man she meets after her relationship with him ends. Hearing of Charlie's reputation as a good-luck charm, women from all over line up for a quick tryst. But when Charlie meets the woman of his dreams, he must find a way to break the curse or risk losing her to the next man she meets.