The story focuses on a group of 6 beautiful women called Thralls, referred to as "the white trash of vampires;" effectively a lower species of vampire. They don't kill people, they don't have the ability to turn their victims into vampires and they can't fly. These Thralls are under the control of Mr. Jones, the vampire who sired them, and whom they are trying desperately to escape. To do this they must complete a blood ritual which will turn them into full-blown vampires. Their plans hit a snag when Ashley, the younger sister of one of the Thralls, comes to visit. Ashley has no idea what her sister has been up to since moving to the big city nor what she has become..

Wunderkind author Mike Dolan achieved literary fame at age 21 with a steamy expose on his seemingly idyllic Maine town. Four years later, he hasn't written another word and reluctantly returns home in search of an antidote ... where he is welcomed back with all the warmth of a lynch mob.

"There are those among us who can move at will between the world of the wolves and the world of the humans. My people call them skin walkers." Seattle police detective John Kanin has a problem. He's in love, but shortly after agreeing to marry him, his girlfriend disapears. His search leads to her home town, where people are clearly hiding information from him. One of the things they are hiding is the fact that they are all werewolves, as is John's girlfriend, Ruby.

High school students Dylan Roberts and Ashley Gordon make the transition from being just friends to dating, while dealing with a whole range of real teen issues of family, friends and relationships.

Anthology series of composed of distinct story episodes, sometimes with a plot twist at the end, with occasional recurring story elements that were often tied together during season-finale clip shows.