Karen never planned on being a hero. A recent widow, she has her hands full with work and parenting her son Max. Then Karen saves Jeremy's life during a drug store robbery and quickly discovers that the young man is intent on paying her back at any cost. At first, life starts improving for this good Samaritan, but as Jeremy's efforts become more extreme, Karen starts to wonder if no good deed truly goes unpunished.

Dr. Bashir Hamed, a Syrian doctor with battle-tested skills in emergency medicine, makes the difficult decision to flee his country and build a new life in Canada with his younger sister Amira. Bash works to navigate a new environment after earning a coveted residency in the Emergency Department of one of the best hospitals in Toronto, York Memorial.