Baron, an imprisoned man, strikes up a friendship with cellmate Otis. As the pair hatch an escape plan together, Baron recalls the story of how he met Marmalade, the love of his life, and their Bonnie and Clyde scheme to rob a bank in order to care for his sick mother and give the couple the life they’ve always dreamed of.

It is 1967, and Larry Gopnik, a physics professor at a quiet Midwestern university, has just been informed by his wife Judith that she is leaving him. She has fallen in love with one of his more pompous acquaintances Sy Ableman.

This drama centers on Hank Chinaski, the fictional alter-ego of "Factotum" author Charles Bukowski, who wanders around Los Angeles, CA trying to live off jobs which don't interfere with his primary interest, which is writing. Along the way, he fends off the distractions offered by women, drinking and gambling.