April, an aspiring journalist, is balancing her ambitious career with her family and a new office romance. In an unexpected twist of fate, April learns that she has leukemia.

The bitter fight for supremacy between the three most popular girls at North Gateway High takes an unexpected turn when their classmate, Tanner, is outed and becomes the school’s first openly gay student. The trio races to bag the big trend in fashion accessories, the Gay Best Friend, while Tanner must decide whether his skyrocketing popularity is more important than the friendships he is leaving behind.