Noah is seeking to reconnect with his outcast brother after the death of their father. He hopes to make amends and share the family's fortune, but instead finds himself in a dark underworld that threatens to tear his family apart. As he struggles to maintain his sanity, Noah is led on a terrifying trail to the truth through a series of cryptic clues.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.