After a young man is bitten on the hand by a radioactive snake, his hand changes into a lethal snake head, which attacks everyone he comes into contact with. Also, his body becomes filled with snakes. Now, he must prevent himself from hurting others.

Refined actress Lauren Ames finally has a chance to study with the great theatre professor Stanislav Korzenowski. Sandy Brozinsky, a brash, loud actress, decides through happenstance to also study with Korzenowski. The two women end up dating the same man (who turns out to be a double agent) and follow him across the country to force him to choose between them.

Five friends get together and decide to plan an operation to rob a bank. The main difference between this and other bank-robbing gangs, however, is that all five men are blind.

Nerdy Hobart Moore is kidnapped by three women, and brought to a house occupied by Gertie, a morbidly obese nymphomaniac. Hobart is more interested in making sure his tropical fish are being fed, than in any of the women.