Murphy is a flawed and irreverent woman who just happens to be blind and is the only “witness” to the murder of her drug-dealing friend, Tyson. When the police dismiss her story, she sets out with her dog, Pretzel, to find the killer while also managing her colorful dating life and the job she hates at Guiding Hope, the guide-dog school owned by her overprotective parents.

A team of young superheroes led by Nightwing (formerly Batman's first Robin) form to combat evil and other perils.

Cady Heron is a hit with The Plastics, the A-list girl clique at her new school, until she makes the mistake of falling for Aaron Samuels, the ex-boyfriend of alpha Plastic Regina George.